Neutron Characterization of BNCT Water Phantom Based on Kartini Research Reactor Using PHITS

Authors

  • Vika Hutaria Universitas Negeri Semarang
  • Susilo Susilo Universitas Negeri Semarang
  • Yohannes Sardjono Pusat Sains Dan Teknologi Akselerator; Badan Tenaga Nuklir Nasional (PSTA BATAN) / Center of Science and Technology of Accelerator; National Nuclear Energy Agency

DOI:

https://doi.org/10.24246/ijpna.v4i1.16-21

Keywords:

BNCT, Water phantom, Neutron, Reactor

Abstract

Boron Neutron Capture Therapy (BNCT) is a therapy that utilizes the interaction of thermal neutrons with a boron-10 core that produces alpha particles and lithium nuclei. The result of this boron reaction has high linear energy transfer (LET).  BNCT has an advantage over other radiation therapy in that it has a high selectivity level. This research was run using PHITS simulation to find out the value of neutron flux spread over a water phantom. The conclusion of the research is the distribution of neutron flux in the water phantom without boron is higher the the distribution of neutron flux in the water phantom containing boron

Downloads

Download data is not yet available.

References

National Cancer Institute : 2016

American Cancer Society. Cancer Facts & Figures 2016. Atlanta: American Cancer Society,Inc

Gónzalez-Soto K, Amgarou K, Lagares J I, Expósito M R, Gómez F, Domingo C, SánchezNieto B, Sánchez-Doblado F. 2013. Neutron distribution in radiotherapy treatment rooms. Dpto. Fisiología Médica y Biofísic

World Health Organization (2016)

IAEA (2014. PACT: Together Against Cancer. PACT Program Office. International Atomic Energy Agency. Venna: International Center.

Monshizadeh M, Kasesaz Y, Khalafi H, Hamidi S. 2015. MCNP design of thermal and epithermal neutron beam for BNCT at the Isfahan MNSR. Progress in Nuclear Energy 83:427-432

Wusko ikna urwatul. 2016. Optimasi kolimator dan dosimetri uji invivo boron neutron capture terapi (BNCT) pada beam port tembus reaktor kartini dengan metode simulasi monte carlo N-particle Extended (MCNPX) Tesis : UGM

Miyatake. et al. (2014). Boron Neutron Capture Therapy with Bevacizumab may Prolong the Survival of Recurrent Malignant Glioma Patients: four cases. Radiation Oncology. Hlm 1-6

Zafer, Akan et al (2015). Boron Neutron Capture Therapy for Breast Cancer. International Journal of Women’s Health and Reproduction Sciences Vol. 3, No. 2

Faghihi F, Khalili S. 2013. Beam shaping assembly of a D–T neutron source for BNCT and its dosimetry simulation in deeply-seated tumors. Radiation Physics and Chemistry 89:1–13.

J.G. Fantidis et. al., Optimised BNCT facility based on a compact D-D neutron generator. Int. J. Radiat. Res., October 2013; 11(4): 207-214. (2013)

J.G. Fantidis et. al., Optimised BNCT facility based on a compact D-D neutron generator. Int. J. Radiat. Res., October 2013; 11(4): 207-214. (2013)

Batan .go.id

Wolfgang A.G. Sauerwein . 2012. Neutron Capture Therapy: Principles and Application. Springer-Verlag Berlin Heidelberg 2012

News Medical Life Science. 2017. Brachytherapy Side Effect.

Cancer Research UK. Treatment.

Department Of Health And Human Services. 2012. What To Know About Brachytherapy (A Type of Internal Radiation Therapy). US : National Institutes of Health

Zafer, Akan et al (2015). Boron Neutron Capture Therapy for Breast Cancer. International Journal of Women’s Health and Reproduction Sciences Vol. 3, No. 2

S. Triviño et al (2016). Neutron Dose Estimation in a Zero Power Nuclear Reactor. Radiation Physics and Chemistry 127 (2016) 62–67. Laboratorio de Investigación e Instrumentación en Física Aplicada a la Medicina e Imágenes por Rayos X (LIIFAMIRx), Universidad Nacional de Córdoba, Av. M. Allende s/n, Córdoba, Argentina

National Cancer Institute (2015). Cancer Treatment. National Institutes of Health Zaidi, Lilia, et al. Monte Carlo based Dosimetry for NCT of Brain Tumor. 1Faculte de physique USTHB, Laboratoire SNIRM, BP 32 EL-Alia. EPJ Web of Conferences 128, 04003:2016h

Downloads

Published

2019-08-14

How to Cite

Hutaria, V., Susilo, S., & Sardjono, Y. (2019). Neutron Characterization of BNCT Water Phantom Based on Kartini Research Reactor Using PHITS. Indonesian Journal of Physics and Nuclear Applications, 4(1), 16–21. https://doi.org/10.24246/ijpna.v4i1.16-21

Issue

Section

Articles