Optimization of Neutron Collimator in The Thermal Column of Kartini Research Reactor for in vitro and in vivo Trials Facility of Boron Neutron Capture Therapy using MCNP-X Simulator

Authors

  • Ranti Warfi Physics Engineering Department, Gadjah Mada University
  • Andang Widi Harto Physics Engineering Department, Gadjah Mada University
  • Yohannes Sardjono Center for Accelerator Science and Technology, National Nuclear Energy Agency
  • Widarto Widarto Center for Accelerator Science and Technology, National Nuclear Energy Agency

DOI:

https://doi.org/10.24246/ijpna.v1i1.54-62

Keywords:

optimization, collimator, BNCT, MCNP-X, in vivo in virtro trials, IAEA’s criteria

Abstract

The optimization of thermal column collimator has been studied which resulted epithermal neutron beam for in vivo and in vitro trials of Boron Neutron Capture Therapy (BNCT) at Kartini Research Reactor of 100 kW by means of Monte Carlo N-Particle Extended (MCNP-X) codes. The design criteria were based on recommendation from the International Atomic Energy Agency (IAEA). MCNP-X calculations indicated by using 5 cm thickness of Ni as collimator wall, 30 cm thickness of Al as moderator, 20 cm thickness of 60Ni as filter, 2 cm thickness of Bi as γ-ray shielding, 3 cm thickness of 6Li2CO3-polyethylene as beam delimiter, and for in vivo in vitro trials purpose, aperture was designed 8 cm radius size, an epitermal neutron beam with an intensity 1.13E+09 n.cm-2.s-1, fast neutron and γ-doses per epithermal neutron of 1.76E-13 Gy.cm2.n-1 and 1.45E-13Gy.cm2.n-1,minimum thermal neutron per epithermal neutron ratio of 0.008,and maximum directionality of 0.73, respectively could be produced. The results have passed all the IAEA’s criteria.

Downloads

Download data is not yet available.

References

Abdi, M. (2012). Collimator Design for Neutron Radiography Systems Using a Reactor Flux. Middle-East Journal of Scientific Research , 11(ISSN 1990-9233), 648-651.

Fatemeh S. Rasouli, S. F. (2012). Design and optimiz ation of a beam shaping assembly for BNCT based on D–T neutron generator and dose evaluation using a simulated head phantom. Applied Radiation and Isotopes, 1-2.

Fatemeh s.Rasouli, S. M. (2011). Design of a model for BSA to meet free bam parameter for BNCT on multiplier system for D-T neutron source. Annals of Nuclear Energy, 1-2.

IAEA. (2001). Current status of neutron capture therapy. Vienna: Applied Radiation Biology and Radiation Dosimetry dan Medical Radiation Physics Section Division of Human Health and Physics Section Division of Physical and Chemical Science.

K W Burn, L. C. (2006). The epithermal neutron beam for BNCT under construction at TAPIRO :Physics. EPS Euroconfrence XIX Nuclear Physics Divisional Confrence, 1-3.

Lucas, G. (2010). MCNP Tutorial. Wincousin: UW-Engineering Physics Department.

M.Ilma Muslih Arrozaqi. (2014). Dasar-Dasar Pemrograman MCNPX. Yogyakarta: Pusat Sains dan Teknologi Akselerator Badan Tenaga Nuklir Nasional.

MacGillivray, G. (2011). Neutron Radiography Collimator Design. Petawawa, Ontario, Canada: Nray Services Inc.

N. Soppera, E. D. (2012). JANIS Book of neutron-induced cross-sections. Issy-les-Moulineaux: AEN-NEA.

Nakagawa, W. A. (2012). Neutron Capture therapy: principles and aplication . London: Springer.

Nina Fauziah. (2013). A Conceptual Design of Neutron Collimator in The Thermal Column of Kartini Research Reactor for Boron Neutron Capture Therapy. Yogyakarta, Indonesia: Departemen Teknik Fisika, Fakultas Teknik, Universitas Gadjah Mada.

Organization, W. H. (2012, Agustus). Internation Agency of Research on Cancer. Retrieved Agusutus 25, 2015, from Internation Agency of Research on Cancer: http://www.iarc.fr/en/media-centre/iarcnews/pdf/Global%20factsheet-2012.pdf

RI, D. K. (2015, Februari 4). Departemen Kementrian Kesehatan RI. Retrieved Agustus 25, 2015, from website Departemen Kementrian Kesehatan RI: http://www.depkes.go.id/resources/download/pusdatin/buletin/buletin-kanker.pdf

SEPPÄLÄ, T. (2002). FIR 1 EPITHERMAL NEUTRON BEAM MODEL. Helsinki: Department of Physical Sciences Faculty of Science University of Helsinki.

Sofia Mubarika, M. M. (2006). Analisis dan Penentuan Distribusi Fluks Neutron Thermal Arah Aksial dan Radial Teras Reaktor Kartini dengan Detektor Swadaya. Jurnal Sains & Matematika (JSM), 14(4), 155-159.

Tribe, T. N. (n.d.). News Tribe. Retrieved SEPTEMBER 2015, 7, from www.thenewstribe.com

Turkoglu, D. j. (2012). Design, Construction and Characterization of an External Neutron Beam Facility at The Ohio State University Nuclear Reactor Laboratory. Ohio: Ohio State University .

W. A. G. Sauerwein, A. Wittig, R. Moss, & Y. Nakagawa. (2012). Neutron Capture Therapy: Principles and Application. Berlin: Springer-Verlag.

World Health Organization. (2015, Februari). Cancer. Retrieved Juli 13, 2015, from http://www.who.int/mediacentre/factsheets/fs297/en/

Downloads

Published

2016-02-28

How to Cite

Warfi, R., Harto, A. W., Sardjono, Y., & Widarto, W. (2016). Optimization of Neutron Collimator in The Thermal Column of Kartini Research Reactor for in vitro and in vivo Trials Facility of Boron Neutron Capture Therapy using MCNP-X Simulator. Indonesian Journal of Physics and Nuclear Applications, 1(1), 54–62. https://doi.org/10.24246/ijpna.v1i1.54-62

Issue

Section

Articles