Design Collimator and Dosimetry of in Vitro and in Vivo Test Using MCNP-X Code
Keywords:
BNCT, MCNPX, collimator, dosimetry
Abstract
Studies were carried out to collimator modelling and dosimetry BNCT of in vitro and in vivo test using MCNP-X code. Collimator modelling performed to obtain neutron beam as required by the International Atomic Energy Agency (IAEA). Dosimetry calculations performed to obtain the results of the dose calculation (dosimetry) in the application of BNCT. Collimator modelling and dosimetry simulations performed with MCNPX program. Neutron sources used for simulation, namely cyclotrons HM-30, energy 30 MeV, the current is 1.1 mA. Collimator modelling utilizes to program MCNPX covers cells target as beryllium, collimator wall (reflector), moderate, filter, gamma-ray shielding, and aperture. The simulation results of the modelling are Φepi 1.02241x1010 n/cm2 s, Df/Φepi 2.36487x10-11 Gy-cm2/n, Dγ/Φepi 4.68416x10-12 Gy-cm2/n, Φth/Φepi 3.76285x10-01, J/Φepi 8.37678x103. Based on the calculation of the dose rate that has been done, the result that the optimal dose rate at a depth of 1cm.Downloads
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References
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Barth, R. F., Vicente, M. G. H., Harling, K. O., Ill, W. S. K., Binns, P. J., Wagner, F. M., Suzuki, M., Aihara, T., Kato, I., Kawabata, S. 2012. Current Status of Boron Neutron Capture Therapy of High Grade Gliomas and Recurrent Head and Neck Cancer. Radiation Oncology 2012 7: 146. USA: BioMed Central Ltd. http://www.ro-journal.com/content/7/1/146
Yura, Yoshiaki and Fujita, Yushei. 2013. Boron Neutron Capture Therapy as a Novel Modality of Radiotherapy of Oral Cancer: Principle and Anti tumour Effect. Oral Science International 10 (2013) 9-14. Japan: Osaka University. http://dx.doi.org/10.1016/S1348-8643(12)00046-8
Heber, E.M., Kueffer, P. J., Lee Jr., M. W., Hawthorne, F., Garabalino, M. A., Molinari, A. J., Nigg, D. W., Bauer, W., Hughes, A. M., Pozzi, E. C. C., Trivilin, V. A., Schwint, A. E. 2012. Boron Delivery with Liposomes for Boron Neutron Capture Therapy (BNCT): Biodistribution Studies in a Experimental Model of Oral Cancer Demonstrating Therapeutic Potential. Radiat Environ Biophys (2012) 51:195-204. doi.10.1007/s00411-011-0399-0
Solleh, M. R. M., Tajuddin, A. A., Mohamed, A. A., Munem, E. M. E. A., Rabir, M. H, Karim, J. A., Yoshiaki, K. 2011. Collimator and Shielding Design for Boron Neutron Capture Therapy (BNCT) Facility at TRIGA Mark II Reactor. Journal of Nuclear and Related Technologies, Vol. 8 No. 2
Syahria, Setiawati, E., Firdausi, K. Sofian. 2012. Pembuatan Kurva Isodosis Paparan Radiasi di Ruang Pemerikasaan Instalasi Radiologi RSUD Kabupaten Kolaka-Sulawesi Tenggara. Jurnal Berkala Fisika Vol. 15 No. 4, October 2014, page 123-132, ISSN: 1410-9662
Minsky, D. M., Valda, A. A., Kreiner, A. J., Green, S., Wojnecki, C., Ghani, Z. 2011. First Tomographic Image of Neutron Capture in a BNCT Facility. Applied Radiation and Isotopes 69 (2011) 1858-1861. Doi:10.1016/j.apradiso.2011.01.030
Shultis, J. K. and Faw R. E., 2011. An MCNP Primer. Manhattan: Kansas State University
Mitsumoto, T., Fujita, K., Ogasawara, T., Tsutsui, H., Yajima, S., Maruhashi, A., Sakurai, Y., Tanaka, H. 2010. Cyclotron-Based Neutron Source for BNCT. Proceedings of Cyclotrons 2010, Lanzhou, China
Published
2016-02-28
How to Cite
Yuniarti, S., Sardjono, Y., & Bilalodin, B. (2016). Design Collimator and Dosimetry of in Vitro and in Vivo Test Using MCNP-X Code. Indonesian Journal of Physics and Nuclear Applications, 1(1), 14-19. https://doi.org/10.24246/ijpna.v1i1.14-19
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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Indonesian Journal of Physics and Nuclear Applications is licensed under a Creative Commons Attribution 4.0 International License.
